Female reproductive health-what the classical haematologist needs to know.

Bannow, Bethany Samuelson; Akpan, Imo; Baldwin, Maureen K · Lancet Haematol · 2026

review · Level V

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Abstract

Haematologists should be prepared to address several key transitions and timepoints during the female reproductive health lifespan to provide safe and equitable care for all patients with haematological disorders. In this Review, we summarise important points for recognition and consideration in the care of patients with lifelong or transient haematological conditions. We include discussions on menarche, pregnancy, menopause, and gender-affirming care, and how these life transitions might impact people with underlying haematological disorders, including an increased risk of iron deficiency with or without anaemia. We focus specifically on the impacts of anticoagulation on menstrual bleeding, thrombosis risk on gender-affirming care, and pregnancy on those with sickle cell disease and inherited bleeding disorders.