Crohn Disease Presenting as Vaginal Discharge in a Patient With Systemic Lupus Erythematosus.

Ries, Alexa G; Samalik, Joann; Nocton, James J; Francis, Jessica; Arkin, Lisa M; Seroogy, Christine M; Young, Kara E; Chiu, Yvonne E · Pediatrics · 2026

case_report · Level V

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Abstract

Crohn disease (CD), a subtype of inflammatory bowel disease, may be complicated by extraintestinal manifestations. Although cutaneous findings are among the most frequent, metastatic Crohn disease (MCD), defined as mucocutaneous CD at sites noncontiguous with the gastrointestinal tract, is rare. Children with MCD are more likely than adults to develop genital inflammation. Case reports describe the vulva, scrotum, and penis as common locations of involvement in children with genital MCD. We report a case of a pediatric patient with systemic lupus erythematosus who developed vaginal discharge as a presenting symptom of MCD in the absence of an anorectal-vaginal fistula. We describe an unusual combination of clinical features and intend to improve awareness of uncommon extraintestinal manifestations of CD.

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