Scalable multiplexed machine learning gas sensor chips for food classification.

Bassil, Carla; Lee, Kichul; Liao, Xun; Krishnan, Divya; Zhan, Yifei; Wijaya, Theodorus Jonathan; Hester, Edward; Kim, Minhyun et al. · Sci Adv · 2026

basic_science · Level V

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Abstract

Multiplexed gas sensor arrays combined with machine learning have unlocked previously inaccessible applications for scent-based sensing. Current platforms are limited by overlapping sensing materials with similar compositions, leading to highly correlated responses, or multistep deposition processes that hinder scalability. In this work, we developed a 16-element monolithic chip with fully distinct sensing layers, enabling a truly heterogeneous array. The system consists of highly sensitive carbon nanotube field effect transistors that are functionalized through a single-step microdispensing method compatible with automated pipetting systems. The resulting chip produces characteristic signal patterns in response to object-specific scent profiles and, when combined with machine learning algorithms, can perform automated object identification. We demonstrate the classification of 16 different objects, including food spoilage and nut allergens, with a 92.6% overall prediction accuracy.

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