123 I-MIBG SPECT/CT Reveals Solitary Dorsal Root Ganglion Metastasis From Neuroblastoma Mimicking Schwannoma on MRI.

Zhang, Keyu; Lv, Cinian; Zhang, Bingyan; Wang, Wei; Yang, Jigang · Clin Nucl Med · 2026

case_report · Level V

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Abstract

A 6-year-old girl with high-risk neuroblastoma achieved a complete response following multimodal therapy. During routine post-therapeutic surveillance, 123 I-MIBG SPECT/CT revealed progressive focal tracer uptake within the right T8-T9 intervertebral foramen. Serial imaging demonstrated interval enlargement of the lesion. On contrast-enhanced MRI, the mass exhibited homogeneous hypointensity on T1-weighted images, hyperintensity on T2-weighted images, and intense, uniform enhancement after intravenous gadolinium administration. Radiologic assessment initially favored a schwannoma. Histopathologic examination of the resected specimen confirmed metastatic neuroblastoma involving the dorsal root ganglion.

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