Loading iron(III)porphyrin as the gas/anion binding site into methylated β-cyclodextrin-incorporated polymer hydrogels.

Nakagami, Atsuki; Nishimura, Shin-Nosuke; Koga, Tomoyuki; Kodera, Masahito; Kitagishi, Hiroaki · Soft Matter · 2026

basic_science · Level V

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Abstract

Per-<i>O</i>-methylated β-cyclodextrin (CD<sup>Me</sup>) was incorporated into an <i>N</i>-acryloylglycinamide (NAGAm) polymer. Hydrogels of the CD<sup>Me</sup> polymer were obtained. Fe<sup>III</sup>TPPS was loaded into CD<sup>Me</sup> inside the hydrogels, in which binding of N<sub>3</sub><sup>-</sup>/NO to Fe<sup>III</sup>TPPS was confirmed. Functions of the Fe<sup>III</sup>TPPS/CD<sup>Me</sup> supramolecular complex as a simple heme protein model were demonstrated in the hydrogels.