Self-Poisoning With Prazosin and Its Off-Label Use in Australia, 2014-2024: Analysis of NSW Poisons Information Centre Data.

Lal, Olivia B E; Buckley, Nicholas A; Cairns, Rose · Med J Aust · 2026

retrospective_cohort · Level III

Where this comes from

Abstract

NSW Poisons Information Centre data identified 1030 deliberate prazosin self-poisonings over 11 years, rising from 13 to 170 per year (2014-2024). Young women predominated, likely due to expanded off-label (but accepted) psychiatric use of prazosin. Better evidence on benefits of off-label use is needed to justify increasing risks.

Medical subject headings