From repair to relay: Human retinal organoids re-couple a severed optic nerve.

Achberger, Kevin; Liebau, Stefan · Cell Stem Cell · 2026

basic_science · Level V

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Abstract

Restoring vision after complete optic nerve transection has long seemed out of reach. In this issue of Cell Stem Cell, Gong et al.<sup>1</sup> now show that human retinal organoids transplanted into the lesion form a chimeric host-graft bridge capable of supporting partial, graft-dependent visual function in adult rats.

Medical subject headings