Modeling human hypothalamic cell diversity through developmental patterning.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 42392046.
- Also identified by DOI 10.1016/j.stem.2026.06.003.
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Abstract
Understanding the cellular diversity of the human hypothalamus has been limited by the lack of accessible models. In this issue of Cell Stem Cell, Abay-Nørgaard et al.<sup>1</sup> demonstrate that temporal control of BMP signaling during human pluripotent stem cell differentiation generates diverse hypothalamic populations, providing a platform to study human hypothalamic development and function.
Medical subject headings
- Hypothalamus
- Pluripotent Stem Cells
- Models, Biological
- Body Patterning