Long-term lessons from MATCH01 macrophage therapy in cirrhosis.

Ding, Bi-Sen; Yang, Biao; Cao, Zhongwei · Cell Stem Cell · 2026

other · Level V

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Abstract

In a long-term follow-up of a phase 1/2 clinical trial, Stuart Forbes and colleagues demonstrate that autologous macrophage therapy improves transplantation-free survival in patients with liver cirrhosis. These findings show the translational value of autologous macrophage-based regenerative therapy for advanced liver diseases.

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