Human stem cell-based embryo model governance: Insights from Japan.

Fujita, Misao; Akatsuka, Kyoko; Ariarakawa, Fujika · Cell Stem Cell · 2026

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Abstract

Despite rapid advances in human stem cell-based embryo model (SCBEM) research, national regulatory frameworks remain limited. On April 1, 2026, Japan implemented revised guidelines extending their scope to encompass human SCBEM research. We examine the revisions, differences from ISSCR guidelines, and practical challenges arising during the international regulatory transition period.

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