Larger Blood Volume Increases Detection of Fastidious Mycobacteria and Fungi in Blood Culture.

Chang-Graham, Alexandra; Ghafghaichi, Laleh; Banaei, Niaz · Clin Infect Dis · 2026

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Abstract

Blood volume impacts the sensitivity of blood culture for diagnosis of bloodstream infection caused by non-fastidious organisms, but its effect on recovery of fastidious organisms is poorly understood. Collecting two Myco/F Lytic bottles, 5 mL of blood each, increased the recovery of fastidious mycobacteria and fungi by 24.1% (7/29).