Photosynthetic medicine: Engineering a plant-derived nanofoundry to power mammalian cells.
basic_science · Level V
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- Record sourced from PubMed, PMID 42425061.
- Also identified by DOI 10.1016/j.cell.2026.05.001.
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Abstract
Mammalian eyes receive constant visible light yet lack photosynthesis. Xing et al. engineer an intact thylakoid grana nanoparticle enabling light-driven NADPH production within corneal cells, restoring antioxidant defenses and interrupting inflammatory cycles in dry eye disease. This work positions borrowed photosynthesis as a therapeutic strategy for oxidative, light-exposed tissue pathologies.