MAC in the 21<sup>st</sup> century: time to personalise?
basic_science · Level V
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- Record sourced from PubMed, PMID 42442991.
- Also identified by DOI 10.1016/j.bja.2026.06.007.
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Abstract
Minimum alveolar concentration (MAC), the main metric for measuring anaesthetic potency and anaesthetic depth commonly used for both inhalational and injectable anaesthetics, has predictive deficiencies. We discuss a recent study showing the stochastic nature of MAC as a measure of anaesthetic depth in an individual, as opposed to a population, in a rodent model.