Matrikines dictate the amplitude of inflammation in smoke-related Streptococcus pneumoniae pulmonary infection.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 42446935.
- Also identified by DOI 10.1172/jci.insight.203605.
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Abstract
Smoking remains a major risk factor for the severity of bacterial pneumonias, although mechanisms driving this injury remain poorly understood. This manuscript provides a new insight on how the smoke-exposed lung and bacteria augment the release of enzymes capable of directly damaging pulmonary tissue, leading to worsening inflammation and tissue damage.
Medical subject headings
- Streptococcus pneumoniae
- Inflammation
- Pneumonia, Pneumococcal
- Smoking