Epigenomic profiling links IGF2 overexpression to anthracycline resistance in colorectal cancer organoids.

Hogenson, Tara L; Phillips, William J; Toruner, Merih D; Poshusta, Zachry S; Almada, Luciana L; Xie, Hao; Carr, Ryan M; Li, Jenny J et al. · JCI Insight · 2026

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Abstract

This study provides evidence of a new treatment approach for colorectal peritoneal metastases, a condition associated with a worse prognosis than other types of metastases.

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