Progress and promise of CAR-T cell treatment in autoimmune diseases.
Level V
Where this comes from
- Record sourced from PubMed, PMID 42475287.
- Also identified by DOI 10.1371/journal.pmed.1005179.
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Abstract
Chimeric antigen receptor (CAR)-expressing cells bear a great potential for the treatment of autoimmune diseases. While numerous challenges persist, recent technological developments have demonstrated the potential for CAR cells to reset dysfunctional immune systems and transform care for patients with autoimmune disease.
Medical subject headings
- Autoimmune Diseases
- Receptors, Chimeric Antigen
- T-Lymphocytes
- Immunotherapy, Adoptive
- Receptors, Antigen, T-Cell