Renal biopsy in patients with diabetes: still going strong after all these years.

Alpers, Charles E · Kidney Int · 2026

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Abstract

The study by Caza et al. is the largest study to date to examine the prevalence of nondiabetic kidney disease in clinically indicated kidney biopsies obtained from patients with diabetes. Nondiabetic kidney disease was identified in patients both with and without concurrent diabetic nephropathy and encompassed a wide spectrum of kidney diseases. Clinical data available at biopsy had limitations for predicting nondiabetic kidney disease and distinguishing affected patients from those with diabetic nephropathy only.

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