Characterizing enteric pathology in MPS IIIA mice suggests disease-specific vulnerability among lysosomal storage disorders.

Ziółkowska, Ewa A; Williams, Letitia; Eultgen, Elizabeth; Kick, Grace R; Ding, Xukai; Sorensen, Alexander; Le, Steven; Doray, Balraj et al. · JCI Insight · 2026

basic_science · Level V

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Abstract

The gastrointestinal symptoms that impair quality of life in childhood neurodegenerative disorders, may be because bowel enteric neurons are also affected.

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