The neuroscience of childhood brain cancers.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 42525784.
- Also identified by DOI 10.1126/scitranslmed.aeg9138.
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Abstract
Nervous system activity drives both normal neurodevelopment and childhood brain cancers through paracrine and synaptic signaling. In childhood gliomas, cancer cells integrate structurally and electrically into neural networks, and neuron-cancer interactions are strongly growth-promoting. Understanding the neuroscience mechanisms regulating childhood brain cancers opens a previously unexplored avenue for much-needed therapeutic interventions.
Medical subject headings
- Brain Neoplasms
- Neurosciences