Benign Hyperplastic Nodule in the Peripheral Zone of the Prostate Mimicking Prostate Cancer on 18 F-PSMA-1007 PET/CT.

Man, Xiaojun; Dong, Changming; Dong, Aisheng; Song, Xiandong · Clin Nucl Med · 2026

case_report · Level V

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Abstract

Benign prostatic hyperplasia mainly arises within the para-urethral transition zone and is rarely seen in the peripheral zone. We describe MRI and 18 F-PSMA-1007 PET/CT findings in a patient with a large benign hyperplastic nodule in the peripheral zone. The benign prostatic hyperplastic nodule appeared as a well-defined mass with heterogeneous signal intensity at T2-weighted images and increased 18 F-PSMA-1007 with SUV max of 7.3. This case indicates that a large benign prostatic hyperplastic nodule can arise from the peripheral zone and shows increased 18 F-PSMA-1007 uptake mimicking prostate cancer.

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