Prolonging the Triplet Excited-State Lifetime via Tandem Through-Space Conjugation in Tetracationic Cyclophanes for Efficient Metal-Free Photoredox Catalysis.

Li, Yawen; Sun, Qi; Wang, Zengrong; Yi, Cui; Cao, Tianle; Zhou, Zhijie; Li, Naiyao; Wei, Wenxin et al. · Adv Mater · 2026

basic_science · Level V

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Abstract

Prolonging the triplet excited-state lifetime is essential for developing efficient photocatalytic systems. Herein, a series of viologen-based cyclophane derivatives (2, 6, and 8) featuring TSC were designed and synthesized, with TSC-boxes 6 and 8 incorporating a unique combination of cyclophane structures and TSC units. Compared with 2 and 6, which possess only a single TSC unit, TSC-box 8 with a tandem TSC structure exhibits enhanced spin-orbit coupling and a narrower singlet-triplet energy gap. These attributes endow TSC-box 8 with favorable photoelectric properties, including photoluminescence and an apparent one-step four-electron redox behavior. Nanosecond transient absorption spectroscopy revealed efficient formation of the triplet excited state, prolonging the triplet excited-state lifetime, thereby enabling effective generation of O<sub>2</sub> <sup>•-</sup> and •OH. As a photocatalyst, TSC-box 8 efficiently mediates metal-free photoredox catalysis, affording benzimidazole derivatives in up to 99% yield and enabling the selective oxidation of toluene to benzaldehyde within 1 h (yield: 90%, conversion: 96%) and to benzoic acid within 5 h (yield: 97%, conversion: 98%). This work provides a strategic approach to designing long-lived triplet excited-state systems for metal-free photocatalysis.