FAPI-negative Papillary Renal Cell Carcinoma With Markedly FAPI-avid Sacral Insufficiency Fracture.

Yerdes, Enes; Sahin, Ertan · Clin Nucl Med · 2026

case_report · Level V

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Abstract

We report a 77-year-old woman with papillary renal cell carcinoma showing no increased [68Ga]Ga-FAPI uptake in the primary tumor, while intense sacral FAPI uptake mimicked bone metastasis. MRI findings and 2-year follow-up supported a sacral insufficiency fracture without metastatic disease. This case highlights fracture-related FAPI uptake as an important oncologic imaging pitfall.