"Heart-in-the-dish" models identify mechanisms of diastolic dysfunction.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 42561902.
- Also identified by DOI 10.1016/j.stem.2026.07.007.
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Abstract
Modeling of cardiac pathologies in tissue-engineered models is coming of age. Two independent studies by Reid et al.<sup>1</sup> and Tani et al.<sup>2</sup> present in-depth multi-phenomics data from a human cardiac organoid (hCO) model and explore hCOs and engineered heart tissues (EHTs) for modeling of diastolic dysfunction.
Medical subject headings
- Diastole
- Tissue Engineering
- Heart