Mapping cell fate in space and time.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 42561904.
- Also identified by DOI 10.1016/j.stem.2026.07.001.
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Abstract
Cellular development unfolds across both space and time, with lineage history influencing cellular identity and tissue organization. In this issue of Cell Stem Cell, Jia et al.<sup>1</sup> combine CRISPR lineage recording with spatial transcriptomics to reconstruct the clonal relationships and spatial organization of cells during mouse development and cancer progression.
Medical subject headings
- Cell Lineage
- Cell Differentiation