Genetic variation in the long pentraxin PTX3 and Dectin-1 does not predispose to influenza- or COVID-19-associated pulmonary aspergillosis.
other · Level IV
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- Record sourced from PubMed, PMID 42566654.
- Also identified by DOI 10.1093/infdis/jiag403.
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Abstract
In this multicentric study, we found no association regarding incidence or outcome between common single nucleotide polymorphisms in PTX3 and CLEC7A and invasive pulmonary aspergillosis in patients with severe viral pneumonia. The distinct pathophysiology of virus-associated pulmonary aspergillosis warrants exploration of genetic variation in novel candidates.