Managing Eosinophilic Gastrointestinal Disorders: Diet, Drugs, and Dilation in the Era of Shared Decision-Making.

Abstract

Eosinophilic gastrointestinal disorders encompass chronic, immune-mediated disorders indicative of eosinophil infiltration and inflammation causing a range of gastrointestinal symptoms. Eosinophilic gastrointestinal disorders are subdivided into the part of the gastrointestinal tract that is involved, including eosinophilic esophagitis, eosinophilic gastritis, eosinophilic enteritis, and eosinophilic colitis. Treatment for eosinophilic gastrointestinal disorders can vary widely, and treatment modalities include dietary intervention, drugs, and endoscopy-based dilation therapy. With these wide range of therapeutic options, shared decision-making with the patient is important for finding the right treatment for each individual patient. In this review, treatment modalities for eosinophilic gastrointestinal disorders will be summarized for both pediatric and adult populations. This review will focus on shared decision-making aspects in treating eosinophilic gastrointestinal disease with balancing efficacy, risks, patient preference, and quality of life.