68 Ga-FAPI-04 PET/CT Findings in Primary Hyperoxaluria Type 1.

Jia, Guorong; Tian, Jinming; Cheng, Chao; Zuo, Changjing; Dong, Aisheng · Clin Nucl Med · 2026

case_report · Level V

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Abstract

Primary hyperoxaluria type 1 is a rare genetic disorder that leads to systemic oxalate deposition and end-stage renal disease. We describe 68 Ga-FAPI-04 PET/CT findings in a case of primary hyperoxaluria type 1. 68 Ga-FAPI-04 PET/CT showed striking FAPI uptake in multiple bones and joints. This FAPI distribution likely represents a unique imaging manifestation of the active fibroblastic repair process triggered by oxalate crystal deposition.

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