How does the hippocampus contribute to the pain experience?

Ayoub, Lizbeth J; Nelson, Sarah; McAndrews, Mary Pat; Moayedi, Massieh · Pain · 2026

basic_science · Level V

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Abstract

Substantial evidence from animal and human studies supports the hippocampus' role in pain, positioning it as a key contributor to the pain experience. Here, we comprehensively incorporate the hippocampus in our understanding of pain perception and provide critical insight and novelty for future interdisciplinary research in pain.

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