Clonal hematopoiesis is associated with progression of idiopathic pulmonary fibrosis.

Asarian, Lori; Jia, Jianlong; Sirokha, Dmytro; Paulini, Lara; Dietel, Daniela; Stoleriu, Mircea Gabriel; Frankenberger, Marion; Yildirim, Ali Önder et al. · JCI Insight · 2026

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Abstract

Clonal hematopoiesis-related mutations associate with rapid IPF progression and lung function decline. Exploring them mechanistically may identify important diagnostic or therapeutic targets for IPF patients.

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