Virtual Cell Challenge 2026: Benchmarking zero-shot generalization across cellular contexts.
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- Record sourced from PubMed, PMID 42648290.
- Also identified by DOI 10.1016/j.cell.2026.08.004.
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Abstract
The Virtual Cell Challenge returns in 2026 with a more demanding test of biological generalization: zero-shot prediction across multiple independent cellular contexts. Participants will build models to predict gene knockdown responses in a new Arc-generated dataset comprising unseen cell lines. The goal is to determine whether the best models can meaningfully close the gap between preclinical experimental predictions and human biology.