An early-life window of opportunity opened by hyocholic acids.
Where this comes from
- Record sourced from PubMed, PMID 42679791.
- Also identified by DOI 10.1016/j.cmet.2026.07.003.
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Abstract
Newborns emerge from a sterile womb into a microbe-rich environment that necessitates balancing immune tolerance with protection. Zheng et al. revealed that hyocholic acids help establish this balance by promoting colonization of beneficial bacteria and modulating T cell differentiation to support immune regulation.<sup>1</sup>.
Medical subject headings
- Humans
- Animals
- T-Lymphocytes
- T-Lymphocytes/immunology
- T-Lymphocytes/cytology
- Immune Tolerance
- Cell Differentiation