Magnetic Resonance Imaging During Therapeutic Hypothermia Accurately Reflects the Degree of Brain Injury in Neonates with Hypoxic-Ischemic Encephalopathy.
retrospective_cohort · Level III
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- Record sourced from PubMed, PMID 42692143.
- Also identified by DOI 10.1016/j.jpeds.2026.115316.
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Abstract
We conducted a retrospective analysis of data collected prospectively from a cohort of 114 neonates with hypoxic-ischemic encephalopathy. Magnetic resonance imaging (MRI) obtained during therapeutic hypothermia (TH) showed 95% concordance with MRI obtained at a median postnatal age of 11 days in regard to injury pattern and severity. These results support MRIs during TH as a reliable tool to assess brain injury, facilitating timely clinical decisions, parental counseling and trial enrollment.