A new name, an old crisis: Metabolic dysfunction at the core of polyendocrine metabolic ovarian syndrome.

Stener-Victorin, Elisabet; Zhao, Han; Azziz, Ricardo; Teede, Helena · Cell Metab · 2026

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Abstract

Affecting hundreds of millions of women worldwide, polyendocrine metabolic ovarian syndrome (PMOS, formerly polycystic ovary syndrome) carries a significantly higher risk of cardiovascular and metabolic diseases. Here we discuss how renaming this disease reframes a profoundly misunderstood condition for which basic metabolic research remains critically underfunded and fragmented.