Post-traumatic Pleomorphic Adenoma of the Scalp: A Case Report and Proposal for Updated Diagnostic Criteria for Trauma-related Neoplasia.

Ganga, Kiran; Del Toro, Emilio; Wunderlich, Jeffrey R; Gosselin, Benoit J; Pettus, Jason R; Huyck, Karen L · J Occup Environ Med · 2026

case_report · Level V

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Abstract

Pleomorphic adenomas classically arise from salivary gland epithelial tissue and may occur after trauma. Criteria for establishing trauma-tumor causation are outdated. This case presents a patient with two separate post-traumatic pleomorphic adenomas and proposes updated criteria for evaluating trauma-related tumor causation. A 59-year-old presented with a frontotemporal scalp lesion one year after workplace head trauma. Nine years earlier she underwent parotidectomy of a pleomorphic adenoma following jaw trauma. The excised scalp lesion was a benign mixed tumor of skin. Histopathologic differences between the scalp and parotid lesions established them as separate primary tumors. The case was evaluated for causation during a workers' compensation claim. The case demonstrates a rare occurrence of multiple post-traumatic benign mixed tumors. We propose an updated and comprehensive set of criteria for objectively assessing trauma-tumor causation.