Progressive multifocal leukoencephalopathy complicating treatment for Wegener's granulomatosis.
case_report · Level V
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Abstract
We describe a man treated with cyclophosphamide and prednisone for Wegener's granulomatosis who developed biopsy proven progressive multifocal leukoencephalopathy (PML). Upon discontinuation of immunosuppression he made a dramatic recovery. As immunosuppressant use is increasing we draw attention to this potentially fatal, but reversible neurologic disease.
Medical subject headings
- Cyclophosphamide
- Granulomatosis with Polyangiitis
- Immunosuppressive Agents
- Leukoencephalopathy, Progressive Multifocal