Anticonvulsant effect of fluoxetine in humans.

Favale, E; Rubino, V; Mainardi, P; Lunardi, G; Albano, C · Neurology · 1995

case_series · Level IV

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Abstract

We report an unblinded, open-label, add-on trial of fluoxetine, a selective serotonin reuptake inhibitor, in 17 patients with complex partial seizures with and without secondary generalization (mean follow-up duration, 14 +/- 1.1 months). Six patients showed complete disappearance of their daily seizures; in the others the seizure frequency was lowered by 30%. No patient reported side effects.

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