Interleukin-10 in the vitreous of patients with primary intraocular lymphoma.
case_series · Level IV
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Abstract
To find an accurate and simple method to diagnose primary intraocular lymphoma. We prospectively analyzed concentrations of interleukin-10, interleukin-1, interleukin-2, interleukin-4, and interleukin-6 in vitrectomy specimens from three patients with primary intraocular lymphoma and five patients with uveitis by enzyme-linked immunosorbent assay. Interleukin-10 in the vitreous was detected in patients with primary intraocular lymphoma. Interleukin-10 levels correlated with clinical activity and the number of malignant cells. Concentrations of interleukin-10 in the vitreous may be a helpful clue to both clinicians and pathologists in diagnosing primary intraocular lymphoma.
Medical subject headings
- Eye Neoplasms
- Interleukin-10
- Lymphoma, B-Cell
- Vitreous Body