Chronic myelopathy associated with human herpesvirus-6.
case_report · Level V
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- Record sourced from PubMed, PMID 7501151.
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Abstract
Human herpesvirus-6 (HHV-6) is implicated in a variety of neurologic diseases. We report a previously healthy elderly woman with progressive spastic paraparesis. At autopsy the spinal cord showed widespread demyelination, axonal loss, and chronic inflammation. HHV-6 DNA was amplified, using polymerase chain reaction, from spinal cord tissue, and glial cells were immunoreactive with an HHV-6 antibody. These findings suggest that HHV-6 may cause myelopathy.
Medical subject headings
- Herpesviridae Infections
- Herpesvirus 6, Human
- Spinal Cord Diseases