Can wound healing be a paradigm for tissue repair?
Level V
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- Record sourced from PubMed, PMID 7519714.
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Abstract
This paper is written in the hope, if not the conviction, that it will be helpful to investigators of muscle physiology and development. Its thesis is that cell growth, connective tissue matrix deposition, and angiogenesis are stimulated in wounds in response to NAD+ depletion caused by a burst in lactate generation. We surmise that muscle development may also involve this metabolic control.
Medical subject headings
- Models, Biological
- Wound Healing