An overview of current pharmacotherapy in perennial rhinitis.

Abstract

Individuals with rhinitis experience significant morbidity due to their disease. Research and clinical care to reduce this suffering are important. To review the pharmacological agents that have been developed for the treatment of perennial rhinitis. Literature review of human studies. Medication classes include antihistamines, decongestants, anticholinergics, cromolyn sodium, and corticosteroids. These vary in regard to their pharmacology, efficacy, and adverse effects. Compliance and cost issues are also critical components of the therapeutic regimen. Carefully chosen pharmacotherapy based on an understanding of the pathophysiology of the disease, knowledge of the potential of medications, and commitment to an ongoing patient/physician education and monitoring program can lead to improved well-being for individuals with perennial rhinitis.