Diagnostic significance of prostate specific antigen and the development of a mass screening system for prostate cancer.
cross_sectional · Level IV
Where this comes from
- Record sourced from PubMed, PMID 7543604.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
The significance of prostate specific antigen (PSA) in the mass screening for prostate cancer was investigated. A total of 4,375 PSA, digital rectal and transrectal ultrasonographic examinations was performed on 3,526 subjects. Among the 3 modalities, PSA had the highest sensitivity (80.4%) and positive predictive value (45.1%). We established age-specific reference PSA ranges for normal Japanese men, and demonstrated the significance of PSA density and PSA velocity. The significance of PSA as a prostate cancer screening modality should be evaluated across multiple age ranges and in combination with previous PSA data and/or prostate volume.
Medical subject headings
- Mass Screening
- Prostate-Specific Antigen
- Prostatic Neoplasms