Tau protein concentrations in cerebrospinal fluid of patients with dementia of the Alzheimer type.
cross_sectional · Level IV
Where this comes from
- Record sourced from PubMed, PMID 7545739.
- Also identified by PMC identifier 486030.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Tau protein concentrations were measured in the CSF of 23 patients with dementia of the Alzheimer type (DAT), 36 patients with multi-infarct dementia (MID), and 23 control subjects. Tau protein concentrations were significantly higher in patients with DAT than in controls (P < 0.001) and patients with MID (P < 0.001). A significantly positive correlation between CSF tau protein and glucose concentrations (r = 0.79, P < 0.001) and evolution of disease (r = 0.47, P < 0.05), and a negative correlation with Folstein's mental state examination test (r = -0.73, P < 0.001) were found in patients with DAT.
Medical subject headings
- Alzheimer Disease
- tau Proteins