Acyclovir-induced neutropenia in an infant with herpes simplex encephalitis: case report.
case_report · Level V
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- Record sourced from PubMed, PMID 7548511.
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Abstract
A newborn infant whose condition was diagnosed as herpes simplex encephalitis and who had subsequent recurrences of skin disease had repeated episodes of neutropenia while receiving therapy with intravenous (30 mg/[kg.d]) or oral (30 mg/]kg.d]) acyclovir. The neutropenia did not recur when the dosage of oral acyclovir was reduced to 10 mg/(kg.d). This case represents the first well-documented report of acyclovir-induced neutropenia.
Medical subject headings
- Acyclovir
- Encephalitis, Viral
- Herpesvirus 2, Human
- Neutropenia