Clarithromycin-induced mania in two patients with AIDS.

Nightingale, S D; Koster, F T; Mertz, G J; Loss, S D · Clin Infect Dis · 1995

case_report · Level V

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Abstract

Acute psychosis was observed in two patients with AIDS who were treated with clarithromycin for disseminated Mycobacterium avium complex infection. The psychosis resolved when treatment with clarithromycin was discontinued and recurred when it was resumed. An adverse response to clarithromycin therapy is a rare but curable cause of acute psychosis in patients with AIDS.

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