Phosphorylase b kinase deficiency glycogenosis with cirrhosis of the liver.

Kagalwalla, A F; Kagalwalla, Y A; al Ajaji, S; Gorka, W; Ali, M A · J Pediatr · 1995

case_report · Level V

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Abstract

We describe an Arab girl with complete absence of phosphorylase b kinase activity in the liver, symptomatic hypoglycemia, and persistently elevated serum aminotransferase values whose symptoms did not lessen with age; sequential liver biopsies showed progression to cirrhosis. Cirrhosis could not be ascribed to any other known cause. We conclude that type IX glycogenosis is not always associated with a benign outcome.

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