Drug delivery: piercing vesicles by their adsorption onto a porous medium.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 7568178.
- Also identified by PMC identifier 40847.
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Abstract
Experimental evidence is presented that supports the possibility of building a "molecular drill." By the adsorption of a vesicle onto a porous substrate (specifically, a lycopode grain), it was possible to increase the permeability of the vesicle by locally stretching its membrane. Molecules contained within the vesicle, which could not cross the membrane, were delivered to the porous substrate upon adsorption. This general process could provide another method for drug delivery and targeting.
Medical subject headings
- Drug Compounding
- Pharmaceutical Preparations