Changes in serum carboxyterminal telopeptide of type I collagen in an experimental model of canine osteomyelitis.
basic_science · Level V
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Abstract
Blood biochemical indices of bone turnover were followed up for 1 month in six dogs with experimental osteomyelitis. The bone infection resulted in significant increase in parameters of bone formation (serum bone alkaline phosphatase and serum osteocalcin) and bone resorption [serum carboxyterminal telopeptide of type I collagen (i-ICTP)] as early as the end of the second week after the operation and inoculation. There was strong evidence that serum i-ICTP levels could be useful for the early diagnosis of postoperative complications in veterinary orthopedics, such as posttraumatic osteomyelitis.
Medical subject headings
- Alkaline Phosphatase
- Bone Development
- Bone Resorption
- Collagen
- Dog Diseases
- Osteocalcin
- Osteomyelitis
- Peptides