Immunophilins and the nervous system.
review · Level V
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- Record sourced from PubMed, PMID 7584950.
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Abstract
The search for immunosuppressant drugs to increase the success of organ transplantation led to the discovery of the immunophilins, proteins that interface with a range of signal transduction systems inside cells, especially in the nervous and immune systems. Here we review how these interesting molecules work and consider their therapeutic potential.
Medical subject headings
- Amino Acid Isomerases
- Carrier Proteins
- DNA-Binding Proteins
- Heat-Shock Proteins
- Immunosuppressive Agents
- Nervous System Physiological Phenomena