Hepatobiliary pruritus: what are effective treatments?

Connolly, C S; Kantor, G R; Menduke, H · J Am Acad Dermatol · 1995

review · Level V

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Abstract

Pruritus is a common symptom in patients with hepatobiliary disease. Numerous treatments have been attempted. We review published therapeutic trials for hepatobiliary pruritus and utilize statistical analysis to evaluate treatment results. Randomized placebo-controlled studies show cholestyramine, rifampin, naloxone, S-adenosylmethionine, prednisolone, and propofol to be effective. Suggestions for future studies of the treatment of hepatobiliary puruitus are proposed.

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