Neuroleptic malignant syndrome in a parkinsonian woman during the premenstrual period.

Mizuta, E; Yamasaki, S; Nakatake, M; Kuno, S · Neurology · 1993

case_report · Level V

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Abstract

A 45-year-old woman with Parkinson's disease developed neuroleptic malignant syndrome (NMS) despite lack of levodopa withdrawal. She experienced two episodes characterized by indomethacin-resistant hyperthermia, hyperhidrosis, and aggravation of parkinsonism. The symptoms, however, disappeared during menstruation. We suggest that the development of NMS may depend, in part, upon the hormonal state.

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